Pain and sleep problems in MSers explained. #MSBlog #Clinicspeak "The following YouTube video from the National MS Society is worth watching. If you have any queries on issues raised please do not hesitate to ask."
METHODS:Self-report survey data was collected for a sample of 1877 individuals with spinal cord injury, neuromuscular disease, postpolio syndrome, or multiple sclerosis. Rates of pain severity and pain interference in these ...
"Neuropathic pain is another form of pain and is typically due to damage of central sensory pathways. When these sensory nerves recover they insert a different type of sodium channel into their membranes to restore electrical ...
Background: Neuropathic pain is a frequent chronic presentation in autoimmune diseases of the nervous system, such as multiple sclerosis (MS) and Guillain-Barre syndrome (GBS), causing significant individual disablement ...
Purpose/Objective: To define the rates of pain, depression, and their co-occurrence in persons with multiple sclerosis (MS). Research Method/Design: Participants were 161 persons with MS who previously participated in ...
The aim of this work is to examine the course and impact of chronic pain and pain-related disability in persons with multiple sclerosis (pwMS) over a 7-year period in the Australian community employing a longitudinal, ...
Methods: We systematically identified prospective studies detailing pain prevalence in definite MS. We used pooled prevalence estimates, explored heterogeneity using meta-regression, and analysed prevalence during the ...
OBJECTIVE: This is a report of a case of central pain successfully treated by epidural placement of spinal cord stimulator electrodes. Neuromodulation of primary afferent fibers and the underlying dorsal root entry zone ...
Patterns of pain-free response in 497 cases of classic trigeminal neuralgia treated with Gamma Knife surgery and followed up for least 1 year. J Neurosurg. 2012 Dec;117 Suppl:181-8. doi: 10.3171/2012.8.GKS121015.
Pharmacological treatment of pain in MS is challenging due to the many underlying mechanisms. Few controlled trials show adequate pain control in this population. Emerging evidence suggests that pain might be more ...
In this clinical and neurophysiological study, we examined the clinical characteristics and underlying mechanisms of neuropathic pain related to multiple sclerosis. A total of 302 consecutive patients with multiple sclerosis ...
Central neuropathic pain in MSers is a common debilitating symptom, which is mostly treated with tricyclic antidepressants or antiepileptics (e.g. gabapentin, carbamazepine, oxcarbamazepine). Unfortunately, the use of these ...
A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis ...
Levetiracetam is an anti-convulsant which is assumed to act by modulating neurotransmitter release via binding to the vesicle protein SV2A. This could have an impact on signalling in the pain pathway. The aim of this study ...
METHODS: Retrospective review of patients having balloon micro-compression (BMC) (n=69) or glycerol rhizotomy (PRGR) (n=67) from 1997-2010. Patients in the two groups were similar with regard to age, gender, pain ...
The pain sensitive structures in the brain that cause headache or the blood vessels (arteries, veins and venous sinuses), meninges (membranous coverings of the brain), cranial nerves, paranasal air sinuses, skull and scalp.
Pain in patients with multiple sclerosis: a complex assessment including quantitative and qualitative measurements provides for a disease-related biopsychosocial pain model. J Pain Res. 2011;4:219-25. Epub 2011 Aug 2.
Outcomes from direct comparisons between different procedures for MS-related TN is lacking. In this study, initial pain-free rates (IPFR), duration of pain-free intervals (PFI) and associated prognostic factors were evaluated.
Hopefully a new treatment for spasticity and pain in MS. Fast Forward and Concert Pharmaceuticals Announce Collaboration to Advance Novel Treatment for Spasticity and Pain in Multiple Sclerosis. Press release March 5, ...
Proportion of MSers with symptoms suggestive of sleep apnea – a potentially serious disorder which causes you to stop breathing repeatedly, often hundreds of times in the night during your sleep = 71%. Proportion of MSers ...
BACKGROUND: The objectives of this cross-sectional study were to assess the prevalence and severity of sleep apnea in MSers referred for overnight polysomnography (PSG) and to explore the radiographic and clinical ...
"Recently I have focused on sleep problems in MS. One particular problem is bladder overactivity at night that results in you having to get up several times to pass urine. There is a treatment for this. The drug is called DDAVP ...
"Last Thursday I made a clinical diagnosis of obstructive sleep apnoea in a MSers attending my clinic. I have now referred this individual for a sleep study. If I am correct treatment for this condition could relieve his daytime ...
BACKGROUND: Poor sleep is a frequent symptom in patients with multiple sclerosis (MS). Sleep may be influenced by MS-related symptoms and adverse effects from immunotherapy and symptomatic medications. We aimed ...
METHODS: Ambulatory MS'ers without a known sleep disorder completed the Short Form (36) Health Survey (SF-36), pain visual analog scale, and two consecutive overnight PSGs. HRQoL was assessed using SF-36 ...
Methods: Demographic and clinical characteristics of unselected consecutive MSers were collected. Different questionnaires were used to assess quality of sleep, daytime sleepiness, fatigue, anxiety, depression and quality of ...
MSers with sleep disorders were offered standard treatment. 56 subjects repeated the questionnaires after ≥ three months, and were assigned to one of three groups: sleep disorders that were treated (SD-Tx, n=21), sleep ...
Objective: We evaluated the relationship of obstructive sleep apnea to fatigue and sleepiness in MS patients.Methods: Ambulatory MS patients without known sleep disorders and healthy controls underwent diagnostic ...
Pain and anxiety are the most common symptoms that affect sleep in MSers. Both of these symptoms are treatable therefore we are letting you down. Please bring this to the attention of your neurologists or specialist nurse.
"Apologies, all the terms used in this post may be foreign to you. This above list is simply a list of all the types of sleep disorders MS'ers may suffer from; some are very rare, whilst other are very common. If you are interested in ...
BACKGROUND: Sleep disruption and fatigue are common in Multiple Sclerosis (MS). Melatonin is one of the major regulators of sleep-wake cycle. The role of melatonin in MS-related sleep disturbances and fatigue as well as ...
BACKGROUND:The objectives of this cross-sectional study were to assess the prevalence and severity of sleep apnea in patients with multiple sclerosis (MS)referred for overnight polysomnography (PSG) and to explore the ...
How do you know if you have a sleep disorder? I suggest you take the following online survey; it should take you less than 2 minutes to complete. Online Sleep Disorders Screening Survey. Or. Complete the following ...
Fatigue is very common in MS and can be attributed to many factors. This paper reviews sleep disturbances in MS and it association with fatigue. In people with significant fatigue sleep hygiene should be on top of the ...
Other features of narcolepsy include rapid onset of a phase of sleep called REM, or rapid eye movement, sleep, cataplexy which is sudden loss of muscle tone with emotion and sleep paralysis; waking-up with the inability to ...