(EPs) is a technique that allows us to test the electrical conduction in a particular pathway within the nervous system. If the conduction is slow it tells us the particular pathway being tested is demyelinated.
EPs can be very helpful in making a diagnosis of MS; EPs can be used to show sub-clinical or asymptomatic involvement of a particular pathway.
Aim: This study assessed combined EPs as a marker and predictor of the disease course of early MS over 3 years.
Methods: 50 MS'ers in the early phase of RRMS prospectively underwent visual, sensory and motor EPs and disability (EDSS) assessments at baseline and at 6months intervals for 3years.
Results: EDSS correlated with the sum of the EPs. The change in the sum of the EPs correlated with the change of EDSS
Conclusions: EPs correlate well with clinical disability in cross-sectional and longitudinal comparison in early MS and allow prediction of disease evolution over a period of 3 years.
"EPs will almost certainly be used to assess remyelination thearpies."
"Do you know what the clinical effects of delayed conduction speed in an the visual pathway?"